Transcriptional Errors in Human Immunodeficiency Virus Type 1 Generate Targets for T-Cell Responses

Keith Garrison; Stephane Champiat; Vanessa York; Ashish Agrawal; Esper Kallas; Jeffrey Martin; Frederick Hecht; Steven Deeks; Douglas Nixon

doi:10.1128/CVI.00410-08

Transcriptional Errors in Human Immunodeficiency Virus Type 1 Generate Targets for T-Cell Responses

Keith Garrison, Stephane Champiat, Vanessa York, Ashish Agrawal, Esper Kallas, Jeffrey Martin, Frederick Hecht, Steven Deeks, Douglas Nixon

Producción científica › revisión exhaustiva

Resumen

We measured T-cell responses to human immunodeficiency virus type 1 (HIV-1) cryptic epitopes encoded by regions of the viral genome not normally translated into viral proteins. T-cell responses to cryptic epitopes and to regions normally spliced out of the HIV-1 viral proteins Rev and Tat were detected in HIV-1-infected subjects.

Idioma original	American English
Publicación	Clinical and Vaccine Immunology
Volumen	16
DOI	https://doi.org/10.1128/CVI.00410-08
Estado	Published - sept 1 2009

Disciplines

Biology

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10.1128/CVI.00410-08Licencia:

http://europepmc.org/articles/PMC2745002?pdf=render

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abstract = " We measured T-cell responses to human immunodeficiency virus type 1 (HIV-1) cryptic epitopes encoded by regions of the viral genome not normally translated into viral proteins. T-cell responses to cryptic epitopes and to regions normally spliced out of the HIV-1 viral proteins Rev and Tat were detected in HIV-1-infected subjects.",

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AU - Martin, Jeffrey

AU - Hecht, Frederick

AU - Deeks, Steven

AU - Nixon, Douglas

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AB - We measured T-cell responses to human immunodeficiency virus type 1 (HIV-1) cryptic epitopes encoded by regions of the viral genome not normally translated into viral proteins. T-cell responses to cryptic epitopes and to regions normally spliced out of the HIV-1 viral proteins Rev and Tat were detected in HIV-1-infected subjects.

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