Transcriptional Errors in Human Immunodeficiency Virus Type 1 Generate Targets for T-Cell Responses

Keith Garrison, Stephane Champiat, Vanessa York, Ashish Agrawal, Esper Kallas, Jeffrey Martin, Frederick Hecht, Steven Deeks, Douglas Nixon

Research output: Contribution to journalArticlepeer-review

Abstract

We measured T-cell responses to human immunodeficiency virus type 1 (HIV-1) cryptic epitopes encoded by regions of the viral genome not normally translated into viral proteins. T-cell responses to cryptic epitopes and to regions normally spliced out of the HIV-1 viral proteins Rev and Tat were detected in HIV-1-infected subjects.

Original languageAmerican English
JournalClinical and Vaccine Immunology
Volume16
DOIs
StatePublished - Sep 1 2009

Disciplines

  • Biology

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